53 results
A study of 853 adults aged 20 to 94 years found antibody architecture broadly preserved, with age-associated signals concentrated in focal targets.A study of 853 adults aged 20 to 94 years found antibody architecture broadly preserved, with age-associated signals concentrated in focal targets.
An XGBoost model reached an AUC of 0.782 in an external cohort of 2,066 older adults to predict basic activities of daily living disability.An XGBoost model reached an AUC of 0.782 in an external cohort of 2,066 older adults to predict basic activities of daily living disability.
Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed Alzheimer model mice.Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed Alzheimer model mice.
The compound directly binds Prohibitin-2 to activate PINK1-PRKN-dependent clearance of damaged mitochondria, easing motor deficits in transgenic mice.The compound directly binds Prohibitin-2 to activate PINK1-PRKN-dependent clearance of damaged mitochondria, easing motor deficits in transgenic mice.