Papers by X L Li

400+ results

  1. Journal of Evidence-based Medicine

    Higher blood pressure is linked to larger brain structures

    In an analysis of 1,012 participants, higher blood pressure was linked to larger deep brain volumes compared with blood pressure below 120/80 millimetres of mercury.In an analysis of 1,012 participants, higher blood pressure was linked to larger deep brain volumes compared with blood pressure below 120/80 millimetres of mercury.

    Cohort study of 1,012 peopleMechanisms
  2. eLife

    Periodic red light exposure eases cellular aging in mice

    In aged mice, periodic red light exposure raised histone acetylation across tissues and reduced SIRT4 levels in skin cells to activate lipid metabolism.In aged mice, periodic red light exposure raised histone acetylation across tissues and reduced SIRT4 levels in skin cells to activate lipid metabolism.

    Experiments in miceInterventions
  3. medRxiv

    Combining DNA and protein scores improves prediction in people

    For numerical traits, combined models increased the measure of variation explained by 0.09–0.66 over DNA scores alone in European-ancestry validation.For numerical traits, combined models increased the measure of variation explained by 0.09–0.66 over DNA scores alone in European-ancestry validation.

    Preprint: cohort study of 36,903 peopleBiomarkers
  4. Journal of Cellular Physiology

    Sestrin1 protects aging livers and aids exercise in mice

    In aged mice, lacking Sestrin1 worsened liver cell senescence and fat buildup, and the protein proved indispensable for the liver benefits of exercise.In aged mice, lacking Sestrin1 worsened liver cell senescence and fat buildup, and the protein proved indispensable for the liver benefits of exercise.

    Experiments in miceExercise
  5. Experimental Gerontology

    Ketogenic diet improved heart function in aged mice

    An eight-week experiment in 22-month-old mice found comparable benefits in males and females given a ketogenic diet rather than standard chow.An eight-week experiment in 22-month-old mice found comparable benefits in males and females given a ketogenic diet rather than standard chow.

    Experiments in miceKetogenic diet