PsyArXiv

A call for a mechanistic-neutral nomenclature replacing “neuromelanin-sensitive” imaging

Preprint: reviewBiomarkers

Abstract

The locus coeruleus (LC) and substantia nigra (SN) have attracted attention in the search for early biomarkers and new therapeutic targets in neurodegenerative and psychiatric diseases. MRI methods that provide contrast in the LC and SN are commonly described as “neuromelanin-sensitive.

The paper