Biomarker-Defined Phenotyping Reveals Patient Heterogeneity Not Captured by a Single Physiological Reserve Score
Preprints.org
Abstract
Background: Patient heterogeneity in routine biomarkers is often collapsed into a single physiological reserve score, but whether that one-dimensional representation holds across acute and chronic settings — or whether it obscures biomarker-defined subgroups relevant to individualized care — is unclear.
The paper
AlTaweel M, Ahmed Jalbani A, Memon F et al.
Preprints.org · 25 Aug 2026 · CC BY · Preprint, not peer-reviewed
