Journal of Alzheimer's Disease

Non-flickering light may improve some memory measures in older adults

A four-week randomised trial in 33 cognitively normal older adults found no measurable group-level differences in recordings of brain electrical activity.

Brain cutaways in dark blue-green and grey show matching intact folds beneath broad light shapes, beside a small group of upright people.
Randomised trial in 33 peopleInterventions

Double-blind, registered NCT06715995

A randomised pilot trial tested non-flickering light stimulation in 33 cognitively normal older adults over four weeks. Researchers assigned 17 participants to stimulation at 40 cycles per second and 16 to a comparison condition at 70 cycles per second. They analysed results from the 29 participants who completed the intervention.

Brain recordings showed no significant differences between groups in the strength of gamma waves, fast electrical rhythms, or how closely activity in different brain regions varied together. This held after both one session and 28 sessions. Additional analyses suggested possible improvements in selected measures of episodic memory—the ability to remember events and experiences—in the 40-cycle group. Both interventions were well tolerated.

Why it matters

The trial addressed whether a drug-free form of sensory stimulation could support cognitive function in aging.

Caveats

The analysis included only participants who completed the intervention. The memory findings came from secondary analyses without statistical adjustment in a small pilot trial.