PopulationsIn silico

Long-Term Impact of Historical BCG Vaccination Policies on Parkinson's Disease Risk: A Hypothesis-Generating Retrospective Cohort Analysis

Figure 1. Selected matrix of single-year birth cohorts generated by interpolation of missing values between actual PD AAIR values from Balash et al., showing quintets of 5 age groups, each presenting their…
Open the figure at full size
Figure 1. Selected matrix of single-year birth cohorts generated by interpolation of missing values between actual PD AAIR values from Balash et al., showing quintets of…Selected matrix of single-year birth cohorts generated by interpolation of missing values between actual PD AAIR values from Balash et al., showing quintets of 5 age groups, each presenting their mean age-adjusted incidence rates (AAIRs) assigned to the mid-age quintet year.Klein et al. · CC BY

Biomedicines

Abstract

Objectives : Adults exposed to the Bacillus Calmette-Guérin (BCG) vaccine demonstrate a reduced incidence of Parkinson's disease (PD). This retrospective study evaluated whether early-life BCG vaccination predicts a long-term reduction in PD incidence during aging.

The paper