Carnosine Potentiates a Compensatory Mitochondrial-Synaptic Proteomic Response in the ALS Cerebellum

Antioxidants

Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive motor neuron degeneration and chronic neuroinflammation in the brain and spinal cord, involving complex interactions between neurons and immune cells.

The paper

Hellen Paula Valerio, Valeria Oliveira, Stephanie Y. Ferreira,
Show 6 more authorsIsabel R. Pereira, Giuseppe Palmisano, Mariana P. Massafera, Vanderson S. Bispo, Fernanda M. Prado, Paolo Di Mascio,
Marisa Helena Gennari de Medeiros

Universidade de São Paulo

Antioxidants · 4 Sep 2026 · CC BY

doi.org/10.3390/antiox15091117PubMed 42792156