BiomarkersHuman trial
Circulating tumor DNA tumor fraction as a biomarker in refractory metastatic colorectal cancer: findings from the CAVE-2 GOIM trial
The Journal of Liquid Biopsy
Abstract
Liquid biopsy guided anti-EGFR rechallenge therapy is gaining ground as a potential option for patient with refractory metastatic colorectal cancer. However, the identification of potential biomarkers to implement patient's stratification is required.
The paper
Davide Ciardiello, Giulia Martini, Luca Boscolo Bielo, Stefania Napolitano
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Gloria Pellizzari, Filippo Pietrantonio, Paola Andena, Silvia Marchesi, Salvatore Pisconti, Claudia Nisi, Giampaolo Tortora, Lisa Salvatore, Andrea Sartore-Bianchi, Salvatore Siena, Federica Papaccio, Marco Messina, Elena Ongaro, Alberto Zaniboni, Carmine Pinto, Lorenzo Antonuzzo, Antonio Avallone, Nicola Normanno, Giuseppe Santabarbara, Maria Giulia Zampino, Alessandra Pia D’Agata, Rossana Berardi, Alessio Aligi Cogoni, Claudio Lotesoriere, Tiziana Pia Latiano, Carminia Maria Della Corte, Nicola Fazio, Giuseppe Curigliano, Roberto Bordonaro, Teresa Troiani, Ferdinando De Vita, Erika Martinelli, Fortunato Ciardiello,European Institute of Oncology · University of Campania "Luigi Vanvitelli"
The Journal of Liquid Biopsy · 17 Sep 2026 · CC BY