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Bioorganic Chemistry

Lipid-conjugated siRNA targeting SARM1 enables CNS silencing and mitigates alzheimer-like phenotypes

By Ying Cai, Qiongqiong Hou, Zihui Cheng, Show 8 more authorsJingshan Shen
Experiments in animalsInterventions
Paper

The paper

Ying Cai, Qiongqiong Hou, Zihui Cheng, Show 8 more authorsJingshan Shen

Shanghai Institute of Materia Medica

Bioorganic Chemistry, 13 Sep 2026

doi.org/10.1016/j.bioorg.2026.110526PubMed 42759390

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