Cardiovascular Research

Dual inhibition of SGLT 1 and 2 by sotagliflozin alleviates intracellular sodium overload and improves cardiometabolic remodelling in uraemic cardiomyopathy

By Megan Young, Anja Karlstaedt, Sanushi Dambure, Dunja Aksentijević

Experiments in animalsInterventions

The paper

Queen Mary University of London

Cardiovascular Research, 11 Aug 2026

doi.org/10.1093/cvr/cvag167 PubMed 42578286

American Journal of Physiology Heart and Circulatory Physiology3 Oct 2026
Mitochondrial proteostasis is impaired in mouse heart failure
Research Square8 Oct 2026
Semaglutide improved heart artery function in pigs