Peak activity linked to lower death risk in diabetes with hypertension
Higher peak activity intensity was linked to lower mortality in UK Biobank adults with both conditions, with an adjusted hazard ratio of 0.43.
Dose-response
Limit: The abstract omits the activity increments represented by the hazard ratios
Edited by Boris Djordjevic · AgingResearch.News
An observational study analyzed wrist-sensor data from 4,294 adults with both diabetes and hypertension in UK Biobank and 530 in a second cohort. It also included 1,482 and 235 adults, respectively, with diabetes alone. Median follow-up in UK Biobank was 85.2 months; mean follow-up in the second cohort was 63.5 months.
Among adults with both conditions, higher peak activity intensity was associated with lower mortality in both cohorts after adjustment for other factors. The reported hazard ratios, measures of relative death rates, were 0.43 and 0.57, respectively. Total daily activity was also linked to lower mortality in UK Biobank, with a hazard ratio of 0.66. In the second cohort, that association was no longer statistically significant after full adjustment.
Why it matters
For people aging with both diabetes and hypertension, the study addresses whether wearable activity measures could help refine assessments of mortality risk.
Caveats
The observational design cannot show that greater activity caused lower mortality. The abstract does not specify the activity increments represented by the hazard ratios.
