Skip to content
AgingResearch.News
  • HomeHome
  • SearchSearch
  • AskAsk
  • FollowingFollowing
  • SavedSaved
AgingResearch.News
AHA Scientific Sessions 2025 Abstract

Ly6C-Targeted LNP Delivery of CAR-ABCA1 mRNA Reprograms Macrophages for Enhanced Efferocytosis and Cholesterol Efflux in Atherosclerosis

By Weiyan Li, Xueyi Weng, Juying Qian
Experiments in animalsInterventions
Paper

The paper

Weiyan Li, Xueyi Weng, Juying Qian

Shanghai Medical College of Fudan University

AHA Scientific Sessions 2025 Abstract, 3 Nov 2025

Presented at AHA Scientific Sessions 2025, abstract 4368865

doi.org/10.1161/circ.152.suppl_3.4368865

Related

  • International Immunopharmacology·3 Oct 2026

    Rapamycin improves efferocytosis and reduces plaques in mice

  • Aging Cell·2 Oct 2026

    Circulating alpha-synuclein promotes atherosclerosis by impairing macrophage autophagy

  • Biomaterials Advances·2 Oct 2026

    Engineered exosome-mimetic nanoparticles improve liver function in aged mice

  • JCI Insight·4 Oct 2026

    Mild caloric restriction accelerates atherosclerosis in mice

PrivacyTermsContact© 2026 AgingResearch.News

    News

    See all
    ER-100 glaucoma trial findings support testing higher dosesTrialsLongevity.Technology and 3 moreNew immune cell map reveals how individual immune aging trajectories divergeResearchMedical Xpress and 2 moreNewer cohorts of older Europeans show slower intrinsic capacity lossResearchThe Lancet Healthy Longevity

    Trials

    See all
    AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of OklahomaSafety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene TechnologyAI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

    Trending

    See all
    Vitamin D deficiencyDiseaseSevere vitamin D deficiency is linked to higher death rates, and 1 more story this weekKetogenic dietInterventionKetogenic diet improved heart function in aged miceNicotinamide ribosideInterventionNicotinamide riboside did not improve early Parkinson diseaseTERTGeneBlood-cell telomerase delays premature aging in zebrafishPregnancyInterventionEstimated brain-age gap rises by three years in pregnancyChildhood lonelinessInterventionChildhood loneliness linked to faster frailty progression

    Topics

    See all
    Mechanisms252Interventions433Biomarkers414Populations545AI & data162Industry & policy18
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News