InterventionsHuman trial

Combining Lifestyle With Metformin to Reduce Dementia Risk: Updates From MET-FINGER Trial

GSA 2025 Abstract

Abstract

MET-FINGER is the first randomized controlled trial combining healthy lifestyle changes with a putative disease-modifying drug (metformin) for the prevention of cognitive impairment, in an APOEε4-enriched at-risk population of older adults.

The paper

FINGERS Brain Health Institute · Karolinska Institutet

GSA 2025 Abstract · 31 Dec 2025 · CC BY

Presented at GSA 2025

doi.org/10.1093/geroni/igaf122.306