GSA 2025 Abstract

Antiretroviral Therapy Alters Skeletal Muscle DNA Methylation in HIV Mice and Promotes Cellular Senescence

Experiments in animalsInterventions

Abstract

HIV-associated morbidity and death have been decreased by antiretroviral therapy (ART), however age-related musculoskeletal frailty is exacerbated in people living with HIV (PLWH) and those on ART, contributing to poor healthspan.

The paper