AD/NEURODEGENERATION BLOOD BIOMARKER ASSOCIATIONS WITH PREVALENT AND INCIDENT MOBILITY AND COGNITIVE IMPAIRMENT

Abstract

Blood biomarkers of Alzheimer Disease pathology (Aβ42, Aβ40, p-tau181) and neurodegeneration (neurofilament light (NFL), glial fibrillary acidic protein (GFAP)) may identify individuals at risk for mobility and cognitive impairment. Among 1751 ARIC study participants at Visit 5 (V5, 2011-13, mean age 76.2 years (5.