AAIC 2025 Abstract

Uncovering regional atrophy not explained by tau deposition using Additional Pathology Inference (AddiPath)

Study in peopleBiomarkers

Abstract

Background: Mixed pathology is prevalent in Alzheimer’s disease (AD) but difficult to detect in vivo as biomarkers for several additional pathologies are in their infancy. Cortical thickness (CT) atrophy reflects both tau deposition and additional pathologies (e.g., TDP‐43).

The paper