Association of Subjective Memory Decline with Objective Memory Decline and Alzheimer’s Related Brain Structure

AAIC 2025 Abstract

Abstract

Background: Subjective memory decline (SMD) is a putative early indicator of Alzheimer’s disease (AD). However, its association with changes in objective memory and AD‐related brain structure is mixed, which may be partly due to reliance on single‐item measures of subjective decline.

The paper