BiomarkersHumans
In vivo detectability of tau‐PET tracers in Alzheimer’s disease
AAIC 2025 Abstract
Abstract
Background: Tau‐PET tracers are essential for visualizing pathology in Alzheimer’s (AD). High detectability to tau is crucial for early detection and monitoring of tau deposition. This study compares the noise to dynamic range ratio (NRR) of [ ¹⁸ F]FTP, [ ¹⁸ F]MK6240, [ ¹⁸ F]PI2620, and [ ¹⁸ F]RO948, cross‐sectionally and longitudinally.
The paper
Cécile Tissot, Nesrine Rahmouni, Hsin‐Yeh Tsai, Suzanne L. Baker
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Joseph Therriault, Arthur C. Macedo, Stijn Servaes, Jenna Stevenson, Firoza Zubeida Lussier, Jacob Ziontz, Peiwei Liu, Lydia Trudel, Brian Andrew Gordon, Belén Pascual, Val J. Lowe, David N. Soleimani‐Meigooni, Hwamee Oh, William E. Klunk, Pedro Rosa‐Neto, William J. Jagust, Tharick Ali Pascoal,Lawrence Berkeley National Laboratory
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025
