BiomarkersHumans
Hormone replacement therapy in women and vascular risk factors modify the association of a multi‐ancestry polygenic risk score with Alzheimer disease and related traits
AAIC 2025 Abstract
Abstract
Background: Alzheimer’s disease (AD) is influenced by genetic and modifiable risk factors, including sex‐specific hormones and vascular comorbidities that may contribute to disparities in disease risk.
The paper
Nuzulul Kurniansyah, Shinya Tasaki, Congcong Zhu, Lindsay A. Farrer
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John Joseph Farrell, Habbiburr Rehman, Richard Sherva, Richard L. Hauger, Victoria C. Merritt, Matthew S. Panizzon, Rui Zhang, J. Michael Gaziano, Jungsoo Gim, Kun Ho Lee, Ricardo A. Vialle, David A. A Bennett, Lisa Laverne Barnes, Annie Lee, Adam Brickman, Carlos C Cruchaga, Paul K. Crane, Eden R. Martin, William S Bush, Richard Mayeux, Jonathan L Haines, Margaret A. Pericak‐Vance, Logue Ma, Timothy J. Hohman, Li-San Wang, Gerald D. Schellenberg, Joanne M. Murabito, Ting Fang Alvin Ang, Rhoda Au, Jesse Mez, Kathryn L. Lunetta, Xiaoling Zhang,Boston University
AAIC 2025 Abstract · 23 Dec 2025 · CC BY
Presented at AAIC 2025
