Audiometric hearing and plasma biomarkers of Alzheimer's disease pathology and neurodegeneration in the Atherosclerosis Risk in Communities Neurocognitive Study

Abstract

Background: Hearing loss is an established risk factor for Alzheimer's disease and related dementias (ADRD) but the mechanism is unknown. We investigated the cross‐sectional association of hearing loss with plasma AD/ADRD biomarkers, hypothesizing that hearing loss is associated with biomarkers reflective of broader neurodegeneration (e.