AAIC 2025 Abstract
Challenges of mediation analysis in a national sample of brain bank donors
By S. M. Keller, W. Ryan Powell, Grace C. George, Show 2 more authorsthe Neighborhoods Study Investigator Team
Study in peoplePopulations
Abstract
Background: Previous work has established relationships between the adverse social exposome, measured by the Area Deprivation Index (ADI), and Alzheimer's disease (AD), TDP‐43, and Lewy body neuropathology, but the mediating effects along the causal pathways underlying these associations are unknown.



