AAIC 2025 Abstract

Challenges of mediation analysis in a national sample of brain bank donors

By S. M. Keller, W. Ryan Powell, Grace C. George, Show 2 more authorsthe Neighborhoods Study Investigator Team
Study in peoplePopulations

Abstract

Background: Previous work has established relationships between the adverse social exposome, measured by the Area Deprivation Index (ADI), and Alzheimer's disease (AD), TDP‐43, and Lewy body neuropathology, but the mediating effects along the causal pathways underlying these associations are unknown.

The paper

University of Wisconsin–Madison

AAIC 2025 Abstract, 23 Dec 2025, CC BY

Presented at AAIC 2025

doi.org/10.1002/alz70860_103598