AAIC 2025 Abstract

The VIVA‐MIND study: Topline Results from Phase 2 RCT of Varoglutamstat in Early AD

Trial in peopleInterventions

Abstract

Background: Varoglutamstat (PQ912) is an oral small molecule inhibitor of glutaminyl cyclases which reduces the pyroglutamate formation of Aβ and CCL2. Preclinical and Ph1 trials support this Ph2 evaluation in early AD.

The paper