AAIC 2025 Abstract

Validating the cortisol hypothesis: Xanamem demonstrates positive clinical effects by lowering CNS cortisol

Trial in peopleInterventions

Abstract

Background: Xanamem TM (Emestedastat) is an oral, selective 11β‐HSD1 inhibitor designed to reduce cortisol production in the brain under development for the treatment of AD.

The paper