BiomarkersHumans
Biomarker and cognitive associates of resistance to neocortical tau pathology in a pooled cohort
AAIC 2025 Abstract
Abstract
Background: Prior evidence suggests that neocortical tau in those with higher β‐amyloid (Aβ) may be the main driver of Alzheimer's disease (AD)‐related neurodegeneration leading to insidious cognitive decline and ultimately a diagnosis of AD dementia.
The paper
Colin J. Birkenbihl, Hannah M Klinger, Michael J Properzi, Rachel F. Buckley
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Madison Cuppels, Jane A. Brown, Gillian Coughlan, Mabel Seto, Annie Li, Jasmeer P. Chhatwal, Bernard Jimmy Hanseeuw, Michelle E. Farrell, Heidi I.L. Jacobs, Maria Carrigan, Oliver Langford, Julie C. Price, Aaron P. Schultz, Dorene M. Rentz, Rebecca England Amariglio, Keith A. Johnson, Reisa Anne Sperling, Michael Donohue, Timothy J. Hohman,Harvard University
AAIC 2025 Abstract · 25 Dec 2025 · CC BY
Presented at AAIC 2025
