Voxel‐wise longitudinal changes between amyloid PET and executive function subcomponents at the preclinical stage of the Alzheimer's continuum

Abstract

Background: Emerging evidence highlights the vulnerability of Executive Function (EF) in subtle cognitive decline, which may precede the clinical onset of Alzheimer's disease (AD). However, how pathological Amyloid (Aβ) accumulation over time relates to EF neuropsychological change remains poorly understood.