BiomarkersHumans
Elevated p ‐Tau217 is Strongly Associated with Longitudinal Neocortical Tau‐PET in Younger Adults: Findings from the A4/LEARN studies and ADNI
AAIC 2025 Abstract
Abstract
Background: The pathophysiological cascade of Alzheimer's Disease(AD) is characterized by amyloid‐β(Aβ) related secretion of soluble phosphorylated tau ( p ‐tau), followed by aggregation of tau tangles and subsequent cognitive decline.
The paper
Gillian Coughlan, Hannah M Klinger, Mabel Seto, Rachel F. Buckley
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Colin J. Birkenbihl, Annie Li, Michelle E. Farrell, Emma G. Thibault, Michael J Properzi, Aaron P. Schultz, Diana L Townsend, Oliver Langford, Jasmeer P. Chhatwal, Hyun‐Sik Yang, Rema Raman, M. A. Donohue, Keith A. Johnson, Reisa Anne Sperling,Harvard University
AAIC 2025 Abstract · 8 Jan 2026 · CC BY
Presented at AAIC 2025
