Cross‐National Study to Operationalize Amyloid, Tau, Neurodegeneration, and Vascular Contributions to Dementia

Abstract

Background: Recent diagnosis and staging criteria have been proposed for AD based on amyloid(“A”), tau(“T”), and neurodegeneration(“N”), with consideration of comorbid vascular(“V”) pathology. However, challenges remain in their application and interpretation for research and clinical use.

The paper