Plasma proteomic signatures of incident mild behavioral impairment – a longitudinal Singaporean memory clinic study

Abstract

Background: Mild behavioral impairment (MBI) is a diagnostic construct capturing neuropsychiatric symptom burden in pre‐dementia subjects, and has been increasingly recognized as an at‐risk entity for dementia [1,2]. However, prognostic biomarkers and mechanistic underpinnings of incident MBI remain unclear.