AAIC 2025 Abstract

Tau‐PET and plasma GFAP association in cognitively unimpaired Aβ‐PET negative individuals

Study in peopleBiomarkers

Abstract

Background: We showed that astrocyte reactivity, as measured by plasma GFAP levels, influences Aβ mediated tau PET pathology in cognitively unimpaired (CU) Aβ‐positive individuals. However, the link between GFAP and tau PET in individuals without detectable Aβ pathology remains elusive.

The paper