Systolic Blood Pressure and Type 2 Diabetes Modify the Relationship Between Alzheimer's Disease Biomarkers and Cognitive/Functional Impairment

AAIC 2025 Abstract

Abstract

Background: Vascular risk factors contribute to Alzheimer's disease (AD) dementia, but their interaction with AD pathology remains unclear. This study examined systolic blood pressure (SYSBP) and Type 2 Diabetes (T2D) as moderators of the relationship between plasma biomarkers and cognitive and functional impairment in older adults.

The paper