AAIC 2025 Abstract

Does sub‐cortical PI‐2620 tau PET signal reflect Alzheimer's disease status?

Study in peopleBiomarkers

Abstract

Background: The first‐generation tau PET tracer AV‐1451 has been widely used to study tau pathology in Alzheimer's disease (AD), but it's high off‐target binding in sub‐cortical structures has limited our ability to examine possible tau pathology in these structures.

The paper

University of Southern California

AAIC 2025 Abstract, 25 Dec 2025, CC BY

Presented at AAIC 2025

doi.org/10.1002/alz70856_104171