APOE ε4 ‐related proteomic profiles in plasma and CSF

Abstract

Background: The APOE ε4 allele ( APOE4 ) is a major genetic risk factor for Alzheimer's disease (AD) and is strongly linked to amyloid‐beta (Aβ) pathology. However, the mechanisms by which APOE4 influences Aβ remain unclear.

The paper