Association of CKM Phenotypic Age Acceleration and APOE Genotype with Risk of Cognitive Decline in U.S. Adults Aged 50 and Over
AAIC 2025 Abstract
Abstract
Background: The association of cardio‐kidney‐metabolic (CKM) syndrome with cognitive decline and APOE genotype remains unclear. This study aimed to investigate the association of CKM phenotypic age (CKMAge) and cognitive decline, considering the effect modification by Apolipoprotein E (APOE) genotype in U.S. adults.

