Functional Connectivity Alterations along the Longitudinal Axis of the Hippocampus in Aging and Alzheimer's Disease

Abstract

Background: The hippocampus, a key region of the limbic system, plays a pivotal role in cognitive decline in Alzheimer's disease (AD). Previous neuroimaging studies revealed that the hippocampus should not be seen as a homogeneous structure but is instead distinctively organized along its longitudinal axis.

The paper