BiomarkersHumans
Decoding Neurodegenerative Disease with NULISA: Disease‐Specific Biomarkers and Predictive Signatures Unveiled
AAIC 2025 Abstract
Abstract
Background: Highly sensitive plasma assays enable accurate blood‐based neurodegeneration biomarkers, offering minimally invasive options for routine clinical use. This study quantified 123 plasma proteins using the Nucleic acid Linked Immuno‐Sandwich Assay (NULISA) platform in over 3,000 individuals with AD, DLB, FTD, PD and controls.
The paper
Katherine Gong, Jigyasha Timsina, Muhammad Ali, Carlos C Cruchaga
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Yike Chen, Menghan Liu, Ciyang Wang, Maulikkumar Patel, Gyujin Heo, Tammie L.S. Benzinger, Suzanne Elizabeth Schindler, John C. Morris, David M. Holtzman, Laura Ibáñez,Washington University in St. Louis
AAIC 2025 Abstract · 24 Dec 2025 · CC BY
Presented at AAIC 2025
