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Sex moderates the association between medial temporal tau pathology and cognitive decline: A multi‐cohort study
AAIC 2025 Abstract
Abstract
Background: Existing positron emission tomography(PET) studies suggest that women exhibit greater regional tau burden than men, but the implications of this sex difference on cognitive trajectories remain elusive. We investigated sex differences on cognitive trajectories as a function of tau burden.
The paper
Annie Li, Hannah M Klinger, Mabel Seto, Gillian Coughlan
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Colin J. Birkenbihl, Michael J Properzi, Michelle E. Farrell, Aaron P. Schultz, Emma G. Thibault, Robert A. Rissman, Diana L Townsend, Kathryn V. Papp, Rebecca England Amariglio, Hyun‐Sik Yang, Rema Raman, Oliver Langford, Michael Donohue, Tobey J. Betthauser, Rebecca E. Langhough, Erin McMullen Jonaitis, Karly Alex Cody, Sterling C. Johnson, Dorene M. Rentz, Keith A. Johnson, Reisa Anne Sperling, Rachel F. Buckley,Harvard University
AAIC 2025 Abstract · 24 Dec 2025 · CC BY
Presented at AAIC 2025



