AAIC 2025 Abstract

Quantifying extracerebral off‐target contamination in [ ¹⁸ F]MK6240 PET imaging using compartmental modeling

Study in peopleBiomarkers

Abstract

Background: [ ¹⁸ F]MK6240 exhibits high affinity to Alzheimer's disease (AD) tauopathy, but meningeal or extracerebral off‐target signal (Figure 1AB) complicates early tau detection.

The paper