BiomarkersHumans
Characterisation of plasma phosphorylated Tau181 in a middle‐aged birth cohort: Associations with cognitive decline, brain structural integrity, and accelerated ageing
AAIC 2025 Abstract
Abstract
Background: Although plasma pTau181 has been shown to accurately identify patients with AD in case‐control studies, its utility as a preclinical biomarker in middle‐aged community‐based cohorts is unclear.
The paper
Ashleigh Barrett-Young, Erin E. Cawston, Brigid Ryan, Reremoana F. Theodore
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Wickliffe C. Abraham, Antony P. Ambler, Tim Anderson, Kirsten R. Cheyne, Elizabeth A. Goodin, Sean Hogan, Renate Houts, David R. Ireland, Annchen R. Knodt, Jesse Kokaua, Tracy R. Melzer, Sandhya Ramrakha, Karen Sugden, Ben Williams, P.D. Wilson, Avshalom Caspi, Ahmad R. Hariri, Terrie E. Moffitt, Richie Poulton,University of Otago
AAIC 2025 Abstract · 24 Dec 2025 · CC BY
Presented at AAIC 2025



