AAIC 2025 Abstract
Gamma‐secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease
Experiments in cellsMechanisms
Abstract
Background: Rare cases of autosomal dominant Alzheimer's disease (ADAD) can provide unique insights into Alzheimer's disease (AD) pathobiology. Pathogenic variants in PSEN1 or PSEN2 are the most common causes of ADAD.
