Association between Neurovascular Coupling Changes and Spatial Navigation Impairment in Individuals with Subjective Cognitive Decline: A 5.0T MRI Study

Abstract

Background: Subjective cognitive decline (SCD) is a high‐risk population for preclinical Alzheimer's disease (AD). Neurovascular coupling (NVC) reflects the complex physiological processes of neuronal activity and cerebral blood flow (CBF), providing new mechanistic insights into neurodegenerative diseases.