MechanismsHumans
Understanding the mechanisms linking GDF15 to dementia risk: A translational approach
AAIC 2025 Abstract
Abstract
Background: Our group previously identified higher growth/differentiation factor‐15 (GDF15) abundance in plasma among individuals who developed dementia (Figure 1a), which was accompanied by altered expression of immune proteins in plasma and cerebrospinal fluid.
The paper
Cassandra Blew, Michael R. Duggan, Dimitrios Tsitsipatis, Keenan A. Walker
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Alison B Herman, Cassandra M Joynes, Jingsha Chen, Mary Kaileh, Ranjan Sen, Aditi Gupta, Krystyna Mazan-Mamczarz, M Gorospe, Alexey E. Lyashkov, Yevgeniya Lukyanenko, Rebecca F. Gottesman, Christie Mitchell Ballantyne, Michael E. Griswold,National Institute on Aging
AAIC 2025 Abstract · 24 Dec 2025 · CC BY
Presented at AAIC 2025
