AAIC 2025 Abstract
Identification of genetic modifiers influencing disease risk in autosomal dominant Alzheimer disease mutation carriers
By Maulikkumar Patel, Arda Cetin, Matthew Johnson, Show 12 more authorsDominantly Inherited Alzheimer Network (DIAN)
Study in peoplePopulations
Abstract
Background: Alzheimer disease participants with autosomal dominant mutations in PSEN1, PSEN2, and APP (ADAD) exhibit variability in clinical presentation (age at onset and clinical symptoms), even within the same family.
