Basal forebrain cholinergic system mediates the impact of serum bile acid profiles on cognitive impairment in Alzheimer's disease

Abstract

Background: Emerging research highlights the role of the gut microbiome in the progress of Alzheimer's disease (AD). Alterations in serum bile acid (BA) profiles, reflecting gut microbial activity, have been observed in AD patients; however, the connection to cognitive decline is still poorly understood.

The paper