California Institute for Regenerative Medicine

• Kyle H. Vining

• Chider Chen

• Keyu Chen

• Yi Chen

• Qinyuan Chen

• Stephanie M Smith

• Boaz Arzi

• Maria M. Soltero‐Rivera

• Jerry Luo

• Ravindra Majeti

Sources: doi.org

• Founded

  1 Jan 2005

Sources: wikidata.org

• NCT06186401

  Collaborator, Phase 1, Recruiting, 20 people, 2 Jan 2024

• NCT04372433

  Collaborator, Phase 1, Completed, 67 people, 4 May 2020

• NCT04119024

  Collaborator, Phase 1, Recruiting, 18 people, 8 Oct 2019

• NCT03249831

  Collaborator, Phase 1, Active, not recruiting, 3 people, 15 Aug 2017

• NCT03240861

  Collaborator, Phase 1, Terminated, 5 people, 7 Aug 2017

• NCT03088878

  Collaborator, Phase 1/2, Completed, 95 people, 23 Mar 2017

• NCT02797470

  Collaborator, Phase 1/2, Active, not recruiting, 11 people, 13 Jun 2016

• NCT02756130

  Collaborator, Phase 1/2, Withdrawn, 0 people, 29 Apr 2016

• Rejuvenate Bio

  US$4m, 1 Jul 2024

Sources: news.google.com

• TorPause: Efficient Static Organ Preservation for Transplants

  DISC2P-11662, 9 Oct 2026

• Neuroepithelial regulation across development, regeneration, aging, and sex

  26 Sept 2026

• The mechanisms and mechanics of aging

  24 Sept 2026

• RNA dysregulation as a determinant of aging and neurodegenerative vulnerability

  DISC4-19291, 8 Sept 2026

• Dynamic Compression Reveals Donor-Age-Associated Inflammaging in Human Mesenchymal Stromal Cell Spheroids

  EDUC4-12792, 7 Sept 2026

• Reversible, Sexually Dimorphic Sympathetic Aging: Distal Axon Withdrawal Shaped by Prepubertal Gonadal Influences

  EDUC4-12756, EDUC5-13853, 7 Sept 2026

• Form and function of actin impacts actin health and aging

  24 Aug 2026

• Inhibiting cyclin D1-CDK6 suppresses senescence-associated inflammatory gene expression and age-related functional decline

  EDUC-4-12813, 20 Aug 2026

• Injectable Thermoresponsive Microgels Encapsulate and Precondition Nucleus Pulposus Cells for Intervertebral Disc Regeneration

  DISC2-14049, EDUC4-12751, 17 Aug 2026

• A Vegan Diet Epigenetically Modulates Inflammatory Pathways and Biological Aging: Genome-Wide DNA Methylation Analysis of a One-Month Isocaloric Vegan Versus Meat-Rich Dietary Intervention

  DISC0‐17507, 3 Aug 2026

• Syndecan-1 Promotes Alveolar Type 2 Epithelial Cell Senescence during Lung Fibrosis

  CIRM EDUC4-12751, 1 Apr 2026

• Proteostasis Stress Drives Stem Cell Aging, Clonal Hematopoiesis and Leukemia

  FA1-00607, 1 Dec 2025

• Paradoxic enhancement of mitochondrial capacity in aging-specific megakaryopoiesis from hematopoietic stem cells

  EDUC4-12759, CL1-00506, FA1-00617, 11 Nov 2025

• Senolytic-sensitive p16Ink4a+ fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

  DISC0-14460, 3 Nov 2025

• Probing DNA damage in Rett syndrome neurons uncovers a role for MECP2 regulation of PARP1

  25 Sept 2025

• A Rare Hematopoietic Stem Cell-Derived Megakaryocyte Progenitor Accumulates via Enhanced Survival and Contributes to Exacerbated Thrombopoiesis Upon Aging

  EDUC4‐12759, 23 Sept 2025

• Autophagy in proteostasis and aging in Caenorhabditis elegans

  18 Sept 2025

• Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging

  TG2 01159, 27 Feb 2023

Sources: api.crossref.org

• Effect of semaglutide on kidney outcomes in the SELECT, FLOW, and SOUL trials: a prespecified pooled analysis

  Grants or research support, 7 Aug 2026

• Autophagy in proteostasis and aging in Caenorhabditis elegans

  Grants or research support, 18 Sept 2025

Sources: pubmed.ncbi.nlm.nih.gov

• Bistable Regulation of Cellular Heterogeneity Governs Thermogenic Activity

  ADA Scientific Sessions 2025 abstract, 13 Jun 2025