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Yeast NAT3 ko diet

Yeast NAT3 ko diet has been studied in 1 paper since 2025: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Jul 10, 2025: “Growth phase diets diminish histone acetyltransferase Gcn5 function and shorten lifespan of Drosophila males”.

Intervention

1 paper studies it2 findingsUpdated

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Japan Agency for Medical Research and Development and 3 more
  • Model organisms1

What did studies of Yeast NAT3 ko diet find?

2

Studies of Yeast NAT3 ko diet measured 2 outcomes; the most studied are GCN5 (1 study) and lifespan (1).

GCN5

downin flies1

1 study

  1. Yeast NAT3 ko diet inhibits GCN5 in flies.

    “remarkably, this diet diminished the function of histone acetyltransferase Gcn5 in larvae.”

    Model organisms

    Growth phase diets diminish histone acetyltransferase Gcn5 function and shorten lifespan of Drosophila males

    EMBO reports

More on GCN5

Lifespan

downin flies1

1 study

  1. Yeast NAT3 ko diet shortens lifespan in flies.

    “A larval diet comprised of yeast nat3 KO shortened the lifespan of male adults”

    Model organismsmales

    Growth phase diets diminish histone acetyltransferase Gcn5 function and shorten lifespan of Drosophila males

    EMBO reports

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