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TIC10

Intervention

1 paper studies it1 finding

PubChem

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Model organisms1

Outcomes

1

Lifespan

upin flies1

1 study

  1. TIC10 extends lifespan in flies.

    “adult-onset administration of TIC10, a compound that reduces the aging-related AKT and extracellular signal-regulated kinase (ERK) signaling pathways, rescues the shortened lifespan of 14-3-3zeta-overexpressing flies”

    Model organismsin 14-3-3zeta-overexpressing flies

    The adaptor protein 14-3-3zeta modulates intestinal immunity and aging in Drosophila

    The Journal of biological chemistry

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