Supervised exercise therapy
Supervised exercise therapy has been studied in 2 papers since 2024: 2 observational studies in people; 1 in the past year. The newest paper, Mar 25, 2026: “Patient participation in supervised exercise therapy and its impact on outcomes and quality of life in peripheral arterial disease”.
2 papers study it6 findingsUpdated
“COD and PWD improved significantly after 6 months (p = .0001 and p = .041)”
None of its findings points the other way.
- 2 independent labs in 1 country
- Humans2
What did studies of Supervised exercise therapy find?
4Studies of Supervised exercise therapy measured 4 outcomes; the most studied are quality of life (1 study), ankle-brachial index (1) and walking performance (1).
Quality of life
no changein humans1
1 study
Quality of life
no changein humans1
Supervised exercise therapy has no effect on quality of life in humans.
“SF-36 scores did not differ significantly”
Human trialperipheral arterial disease Fontaine stage IIn = 190
VASA. Zeitschrift fur Gefasskrankheiten
Ankle-brachial index
no changein humans1
1 study
Ankle-brachial index
no changein humans1
Supervised exercise therapy has no effect on ankle-brachial index in humans.
“whereas ABI showed no significant changes.”
Human trialperipheral arterial disease Fontaine stage IIn = 190
VASA. Zeitschrift fur Gefasskrankheiten
Walking performance
upin humans1
1 study
Walking performance
upin humans1
Supervised exercise therapy improves walking performance in humans.
“COD and PWD improved significantly after 6 months (p = .0001 and p = .041)”
Human trialperipheral arterial disease Fontaine stage II6 monthsn = 190
VASA. Zeitschrift fur Gefasskrankheiten
Major adverse cardiovascular events
no changein humans1HR 0.88
1 study
Major adverse cardiovascular events
no changein humans1HR 0.88
Supervised exercise therapy has no effect on major adverse cardiovascular events in humans (HR: 0.88; 95%CI: 0.423-1.629; P = 0.73).
“However, there was no reduction in the risk of MACE (HR: 0.88; 95%CI: 0.423-1.629; P = 0.73).”
Humansin patients with intermittent claudication, cardiometabolic multimorbidity, and sarcopenian = 82
Annals of vascular surgery
What is Supervised exercise therapy linked with?
2Studies link Supervised exercise therapy with 2 measures, most often major adverse limb events (1 study) and chronic limb-threatening ischemia (1).
Major adverse limb events
downin humans1HR 0.21
1 study
Major adverse limb events
downin humans1HR 0.21
Supervised exercise therapy lowers the risk of major adverse limb events in humans (HR: 0.21; 95% CI: 0.057-0.775; P = 0.02).
“and a reduced risk of MALE (HR: 0.21; 95% CI: 0.057-0.775; P = 0.02).”
Humansin patients with intermittent claudication, cardiometabolic multimorbidity, and sarcopenian = 82
Annals of vascular surgery
Chronic limb-threatening ischemia
downin humans1HR 0.23
1 study
Chronic limb-threatening ischemia
downin humans1HR 0.23
Supervised exercise therapy lowers the risk of chronic limb-threatening ischemia in humans (HR: 0.23; 95% CI: 0.07-0.69; P = 0.02).
“Completion of SET was associated with slower progression to CLTI (HR: 0.23; 95% CI: 0.07-0.69; P = 0.02)”
Humansin patients with intermittent claudication, cardiometabolic multimorbidity, and sarcopenian = 82
Annals of vascular surgery