Sub-bundle tractometry

Intervention1 paper3 findings

A human preprint study reports that sub-bundle tractometry increases white-matter microstructural homogeneity and identifies more clinical group differences in late-life depression and more age-correlated bundles in elderly controls.

  • Humans1

Outcomes

3

Microstructural homogeneity

upin humans1Very low certainty

1 study
  1. Sub-bundle tractometry increases microstructural homogeneity in humans (p < 0.001).

    Humanswhite matter

    Automatic sub-bundle tractometry reveals localized microstructural variations in complex white matter topographies · arXiv · 25 Sep 2026 · Preprint

Clinical group differences

upin humans1Very low certainty

1 study
  1. Sub-bundle tractometry increases clinical group differences in humans (FA: 6 vs. 4; IFW: 23 vs. 17).

    Humanslate-life depression

    Automatic sub-bundle tractometry reveals localized microstructural variations in complex white matter topographies · arXiv · 25 Sep 2026 · Preprint

Age-correlated bundles

upin humans1Very low certainty

1 study
  1. Sub-bundle tractometry increases age-correlated bundles in humans (11 vs. 5).

    Humanselderly controls

    Automatic sub-bundle tractometry reveals localized microstructural variations in complex white matter topographies · arXiv · 25 Sep 2026 · Preprint

Age-correlated bundles →

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