Stressful social roles

2 papers2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

2 independent labs in 1 country

Humans2

Outcomes

Sleep health

downin humans1

1 study

Stressful social roles impair sleep health in humans.
“stress from social roles negatively impacts sleep health”
Humansamong women experiencing menopausefemales
From Risk to Resilience: Multidimensional Influences on Health and Well-Being in Later Life
GSA 2025 abstract31 Dec 2025

Associations

Women's Health Initiative Insomnia Rating Scale

upin humans1

1 study

Stressful social roles are associated with Women's Health Initiative Insomnia Rating Scale in humans (0.09 unit increase, SE = 0.01, p < 0.001).
“Each additional role perceived as stressful was associated with a 0.09 unit increase in WHIIRS (SE = 0.01, p < 0.001).”
Humansunadjusted for depressive symptomsfemalesn = 1,690
The Association Between Stressful Social Roles and Sleep Quality Among Peri- and Post-Menopausal Women
GSA 2025 abstract31 Dec 2025

More on Women's Health Initiative Insomnia Rating Scale