SR29384 and SR31133

Intervention1 paper2 findings

  • Animals1

Outcomes

2

Cellular senescence

downin mice1Very low certainty

1 study
  1. SR29384 and SR31133 decreases cellular senescence in mice.

    Animalsmouse models of aging

    Two compounds improved health-related measures in aging mice · Aging cell · 1 Oct 2026

Cellular senescence →

Senolytic activity

upin mouse cells1Very low certainty

1 study
  1. SR29384 and SR31133 increases senolytic activity in mouse cells.

    Cellssenescent cells

    Two compounds improved health-related measures in aging mice · Aging cell · 1 Oct 2026

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Aging CellAnimals

Two compounds improved health-related measures in aging mice

Experiments in mouse models of aging found reduced tissue senescence, in which cells stop dividing, alongside improvements in measures linked to…Experiments in mouse models of aging found reduced tissue senescence, in which cells stop dividing, alongside improvements in measures linked to healthy lifespan.